Systems and Methods for a Linearly Filled Nuclear Imaging Phantom

A redesigned Derenzo style phantom that requires less radioisotope doped fluid volume and total radioactivity.
Technology No. P160082US01

Overview: Nuclear imaging systems (e.g., SPECT, PET) commonly use imaging phantoms for quality assurance. One such phantom, called a Derenzo style phantom, is used in clinical and research applications to test resolution. The design features triangular hole (or “rod”) patterns drilled into a cylinder, which is placed inside a chamber and submerged in radioisotope doped fluid.

Several problems, including incomplete filling and air bubbles, can make it difficult or impossible to image the phantom. Moreover, a significant volume of fluid is wasted because the entire chamber must be filled. Since the radioisotopes used in these phantoms represent a significant cost to research and clinical institutions a more efficient design is clearly needed. Further, a reduction in personnel dose may be effected by eliminating the “dead volume” of radioactivity in the reservoirs surrounding the phantom pattern.

The Invention: Collaborators from UW–Madison and the Morgridge Institute for Research have developed a new Derenzo style phantom with an interconnecting channel pattern. This enables the phantom to be filled linearly, with fluid flowing continuously through each of the passages. Compared to current methods, linear filling is simpler, faster and safer as it reduces the amount of radioactivity that is needed.

Applications:

  • Quality control phantom for SPECT and PET
  • Useful in research scanners as well as clinical trials requiring multisite cross-brand calibration

Key Benefits:

  • Uses less radioactive filling material
  • Reduces cost
  • Less dose to technicians
  • Piece-wise design is simple to fabricate, take apart and maintain.

  • expand_more mode_edit Authors (3)
    Benjamin Cox
    Mohammed Farhoud
    Stephen Graves
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